Centrioles Position the Nucleus and One Another

Centrioles Position the Nucleus and One Another

1190 Centrioles are among the simplest structures within the eukaryotic cell, but they play a surprisingly complex set of roles. They are composed of nine parallel protein rods, which form ribbed, hollow tubes with more than a passing resemblance to microscopic rigatoni. In pairs, centrioles form the heart of the centrosome, which hovers near the nucleus and coordinates chromosome division duri...

Another one bites the dust…

Last week, I received one of those dreaded annual emails. That’s right, the now almost routine one asking faculty to voice their support, or lack thereof, for the ever-declining number of hard copy journals still being purchased by the library. As an associate professor of public health recently promoted to chair of the department, I appreciate their position, of course. The dominance and ease ...

Another One Bites the Dust

Give Me Another One!

We investigate the complexity of an optimization problem in Boolean propositional logic related to information theory: Given a conjunctive formula over a set of relations, find a satisfying assignment with minimal Hamming distance to a given assignment that satisfies the formula (NearestOtherSolution, NOSol). We present a complete classification with respect to the relations admitted in the for...

Another One Bites the Dust![1]

The contemporary landscape is rife with ruins, from circumscribed tourist attractions to urban decay and demolition sites. When examined, our aesthetic experience of these sites ranges from historical distancing to the sublime and, when found in our local communities (e.g., Providence, RI), to discomfort, displacement, and horror. In particular, this paper is interested in how certain forms of ...